I Didn't Know That!

According to Jen's husband at Snowball's Chance ...

The last player ever to get a hit off Satchel Paige was another Hall-of-Famer, Carl Yastrzemski, who four years earlier made his Major League debut....against the Kansas City Athletics.

Wikipedia has more ...

In 1965, Kansas City Athletics owner Charles O. Finley signed Paige, 59 at the time, for one game. On September 25, against the Boston Red Sox, Finley invited several Negro League veterans including Cool Papa Bell to be introduced before the game. Paige was in the bullpen, sitting on a rocking chair, being served coffee by a “nurse” between innings. He started the game by getting Jim Gosger out on a pop foul. The next man, Dalton Jones, reached first and went to second on an infield error, but was thrown out trying to reach third on a pitch in the dirt. Carl Yastrzemski doubled and Tony Conigliaro hit a fly ball to end the inning. The next six batters went down in order, including a strikeout of Bill Monbouquette. In the fourth inning, Paige took the mound, to be removed according to plan by Haywood Sullivan. He walked off to a boisterous ovation despite the small crowd of 9,000. The lights dimmed and, led by the PA announcer, the fans lit matches and cigarette lighters while singing “The Old Gray Mare.”